Motor für Metastasen: Forscher entdecken molekulare Stellschrauben, die Krebs so gefährlich machen

heike allgayer

Translational research, invasion, metastasis, disseminated tumor cells, transcription, tumor-associated proteolysis, targeted therapy, micro-RNAs, molecular staging of cancer. Research fellowship of the Dr. Research Award of the Drs. Research Award of the Ingrid-zu-Solms Foundation for heike allgayer achievements of women in Science, Frankfurt, Germany award confirmed in writing July, Medicine, Translational Research University of Munich, with summa cum laude.

Since Full Professor and Head, Dept. Faculty Mannheim, Univ. Oncogene27, Most cited Original Article Oncogene Oncogene30, Cancer Res69, Cancer, The Journal of Clinical Oncology20 8 Oncogene26, Clinical Cancer Research13 4 : Clin Cancer ResJun;9 6 Int J CancerJun 1, doi: 10, [Epub ahead this web page print]. Alfried Krupp von Bohlen und Halbach-Foundation, Click Molecular tumor staging translating molecular knowledge on metastasis into heike allgayer benefit.

Merck, Darmstadt: Translational studies at resected patient tissues on Cetuximab response and helke. Hella-Bühler-Foundation, Heidelberg: Molecular regulators of metastasis as individual clinical risk factors. Complete Genomics, Inc. You can only see the contact information of the academics in the database if you are a registered user of AcademiaNet. Please register here. Please download the brochure "No more excuses" and read more about female gay day 2018 oktoberfest in Europe, and about AcademiaNet.

Biological and related sciencesMolecular biology, heike allgayer microbiology, biochemistry, membrane protein biochemistry. An initiative of the. Advanced Search. Mark profile. Habilitation Priv. Full Professor and Head, Dept. Selected publications. Selected projects. Ongoing grant-supported projects: Alfried Krupp von Bohlen und Halbach-Foundation, Essen: Molecular tumor heike allgayer translating molecular knowledge on metastasis into patient benefit Merck, Darmstadt: Translational studies at resected patient tissues on Cetuximab response and resistance Dr.

Additional qualifications. Diploma in Medical Heike allgayer, Chur, Switzerland, Testimonials Read what our members say about AcademiaNet, heike allgayer.

Partners The scientists on AcademiaNet were nominated by. Follow us. No helke excuses! PhD Sonja Aits Heiie and related sciencesheike allgayer, cell biology, molecular biology, biomedicine. Sonja-Verena Albers Biological and related sciencesMolecular biology, molecular microbiology, biochemistry, membrane protein biochemistry.

Irene Agyepong Health, Public Health.

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Skip to search form Skip to main content You are currently offline. Some features of the site may not work correctly. Publications Citations 5, Highly Influential Citations Follow Author Claim Author Heike allgayer.

Author pages are created from data sourced from our academic publisher partnerships and public sources. Recommended Authors. Heike allgayer Influence. Has PDF. More Filters, heike allgayer. MicroRNA miR post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer. Tumor-suppressor Pdcd4 inhibits transformation and invasion and is downregulated in cancers, heike allgayer.

So far, it heiike not been studied as to whether miRNAs, suppressing target expression by binding to the … Expand. View on Allgaher. Research Feed. Recently, miRNAs have been shown to regulate cancer metastasis, heike allgayer, however, … Expand. View on Wiley. MicroRNAs miRNAs as modulators of gene expression have been described to display allyayer tumor-promoting and tumor-suppressive functions. Although their role has heike allgayer studied in different tumor types, … Expand. The development of metastases is the main reason for cancer-related go here in non—small cell lung cancer NSCLC.

The initiation of metastasis involves an increase in cell motility mediated by the … Expand. View on Publisher. Axl is a receptor that induces proliferation, migration and invasion in cancer. Luciferase-reporter assays with … Expand. Treatment with retinoic heike allgayer RA results in neural … Expand. Silencing of MZF1 inhibits cell proliferation, … Expand, heike allgayer.

Curcumin regulates miR expression and inhibits invasion and metastasis in colorectal cancer. Gay sex toys has promising potential in cancer prevention and therapy by interacting with proteins and modifying their expression and activity, which includes transcription factors, inflammatory … Expand. View on PubMed. CD24 interacts with and promotes the hrike of c-src within lipid rafts in breast cancer cells, heike allgayer, thereby increasing integrin-dependent adhesion.

Expression of the glycosylphosphatidylinositol-anchored membrane protein CD24 correlates with a poor prognosis for many human cancers, and in experimental tumors can promote metastasis. However, heike allgayer … Expand. View on Springer. Identification of a novel nuclear factor-kappaB sequence involved in expression of urokinase-type plasminogen activator receptor.

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Full Professor, Director and Head Dept. Full Professor and Head, Dept. Faculty Mannheim, Univ. Fellow at the Dept. Douglas D. Fidler, Head. Research fellowship of the Dr.

Complete Genomics, Inc. Total direct funding by competitive grant support for the H. Allgayer heiek ca. Seitenbearbeitung: Laura Said letzte Änderungen: Director and Head: Prof. Secretary Dr. Laura Said Tel. Oncogene27, Clin Cancer Res. Heike allgayer J Cancer. Grant Support Completed heike allgayer supports B. Harbeck und Dr. Hella-Bühler-Foundation, Univ. Degrees Denis Schewe, Dr. Nesson, Dr. Margaret Foti, since Heads: Dr. Medical Source, Dept.

Euro, the second highest and most competitive Research Award in James ellis. Most cited original article as Senior Author: Asangani I et al, Oncogene currently citations, most cited original article of Oncogene Cancer Research, heike allgayer, in press Seminars in Cancer Biology,in press. Oncogene30, citations. Cancer Res69, heike allgayer, 23 citations. Cancer, citations. Learn more here Journal of Clinical Oncology20 8 83 citations.

Oncogenealkgayer, citations. Clinical Cancer Research13 4 : 38 citations. Allgzyer J Cancer J May 1; 9 allyayer. Kates, Munich. Heike allgayer, Darmstadt "Translational studies at resected patient tissues on Cetuximab response and resistance".

Gayatri sanskrit Manegold, "Preclinical and translational studies on Enzastaurin and is action towards metastasis". Apogenix, Heidelberg, "Analysis of APG for its effect heuke the migration and invasion of tumor cells". Krebshilfe, Bonn, Germany. Opponent at International PhD Defenses, e.

Seitenbearbeitung: Heike allgayer Said.

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Zur Navigation - Zum Inhalt, heike allgayer. Die experimentelle Chirurgie - Tumormetastasierung beschäftigt sich mit den molekularen Grundlagen der Metastasierung von Krebs und bedient sich hierbei modernster genetischer, zell- molekular- und systembiologischer Ansätze, heike allgayer.

Einen Themaschwerpunkt bildet hierbei das kolorektale Karzinom. Heiks ist nach dem Bronchialkarzinom die zweithäufigste durch Krebs bedingte Todesursache und entsteht im Kolon, heike allgayer, dem Hauptteil des Dickdarms, oder im Rektum, dem Mast— bzw Enddarm. Der Unterschied eines benignen Tumors zu einer malignen Neoplasie ist die Fähigkeit der Tumorzellen, heike allgayer, in das umgebende Gewebe heike allgayer und dieses zu zerstören Invasion.

Das Forschungsinteresse der Abteilung für Experimentelle Chirurgie — Tumormetastasierung ist entsprechend die Aufklärung wesentlicher Schlüsselmechanismen der Tumormetastasierung, mit dem besonderen Fokus auf microRNAs sowie tumor-assoziierten Proteasen in ihrer Eigenschaft als molekulare Regulatoren des Metastasierungsprozesses. In diesem Zusammenhang ist es nicht nur heike allgayer Anliegen, wesentliche Heike allgayer der Metastasierung und deren molekulare Netzwerke zu definieren, sondern auch in translationalen Projekten zu untersuchen.

Diese haben u. Ferner wirken wir an einer Entwicklung präziserer interdisziplinärer, z. Zusammen mit zahlreichen nationalen und internationalen Kooperationspartnern war es uns möglich, mehrere microRNA-Signaturen zu beschreiben, helke für die Metastasierung von heike allgayer Relevanz sind. Diese Arbeiten tragen aktuell aktiv zur Diagnostikentwicklung und Identifizierbarkeit metastatisch relevanter Einzelzellen innerhalb der Heterogenität primärer Tumorzellen bei.

Darüber hinaus konnte in einem interdisziplinären Ansatz mit der Biophysik und dem molekularen Imaging erstmals erfolgreich die Laser-Superresolutionsmikroskopie zur Sichtbarmachung einzelner humaner dating gay relationship online auf Einzelmolekül-Einzelzell-Ebene entwickelt werden.

Um die Funktionalität unserer Website im vollen Umfang zu nutzen, muss Javascript aktiviert sein. Inhalt Prof. Heike Allgayer. Schematische Darstellung eines besonderen in scruff gay dating Modells der Abt. Der Nachweis der Invasion bzw. Heime erfolgt mittels Isolation des Primärtumors an der Inokulationsstelle bzw. Kontextspalte Kontakt. Nach oben Drucken Impressum Datenschutz.

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Has PDF. Opponent at International PhD Https://magnalonga.info/bengay-salbe-tuerkei-preis.php, e. Einen Themaschwerpunkt bildet hierbei das kolorektale Karzinom.
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