Of recurrance of breast cancer

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Some breast cancers return decades later. Now, a researcher at Stanford, joined by collaborators at several other institutions, has subcategorized tumors to predict recurrence, guide treatment decisions and improve drug development. Christina Curtis and her collaborators have developed a tool with the potential to help physicians predict which breast cancer patients are at high risk for recurrence.

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By Charlotte Bath January 25, Advertisement. King is the Anne E. The symposium was hosted by the Robert H.

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Recurrent breast cancer is breast cancer that comes back after initial treatment. Although the initial treatment is aimed at eliminating all cancer cells, a few may have evaded treatment and survived. These undetected cancer cells multiply, becoming recurrent breast cancer.

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Breast cancer remains a deadly disease, even with all the recent technological advancements. Breast cancer recurrence is clinically a huge problem and one that is largely not well understood. Over the years, a number of factors have been studied with an overarching aim of being able to prognose recurrent disease.

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The return of breast cancer after a period of remission, referred to as a recurrenceoccurs when cancer cells remain after treatment despite best efforts to eradicate them. These lingering cells can often remain dormant for years and, for reasons not entirely understood, suddenly start to multiply. A recurrence may develop in the same area as the first malignancy, in the opposite breast, or in some other part of the body.

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For some women, breast cancer may come back after treatment — sometimes years later. This is called a recurrence. Recurrence can be local in the same breast or in the surgery scarregional in nearby lymph nodesor in a distant area.

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Recurrent breast cancer BC after initial treatments is usually associated with poor outcome. The objective of this study is to evaluate baseline characteristics of BC patients to determine their prognostic influence of recurrences. In this retrospective study of BC patients, patients who had recurrence within the first, second, or third 5 years after diagnosis were included in the study.

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The recurrence of breast cancer is something no one wants to face. The majority of individuals diagnosed with breast cancer will never experience recurrence of their disease. However, if it does happen, breast cancer recurrence can be effectively treated most of the time.

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Steady rates of recurrence in women with estrogen receptor-positive disease could influence decisions about long-term therapy. Even 20 years after a diagnosis, women with a type of breast cancer fueled by estrogen still face a substantial risk of cancer returning or spreading, according to a new analysis from an international team of investigators published in the New England Journal of Medicine. Standard treatment for estrogen receptor-positive, or ER-positive, breast cancer includes five years of the endocrine-based treatments tamoxifen or aromatase inhibitors, both of which are taken daily as a pill.

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A breast cancer recurrence, or "recurrent breast cancer," is cancer that has come back in the same or opposite breast or chest wall after a period of time when the cancer couldn't be detected. During surgery to remove an original diagnosis of breast cancer lumpectomy or mastectomythe surgeon removes all the cancer that can be seen and felt. But tests for cancer aren't sensitive enough to detect tiny groups of cancer cells that may be left over after surgery. It is possible for isolated groups of cells to survive radiation therapy and chemotherapy intended to reduce the risk of recurrence.


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